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Veronick Benoy Selected Research

Histone Deacetylase 6

1/2021Tetrahydroquinoline-Capped Histone Deacetylase 6 Inhibitor SW-101 Ameliorates Pathological Phenotypes in a Charcot-Marie-Tooth Type 2A Mouse Model.
1/2019Brain Penetrable Histone Deacetylase 6 Inhibitor SW-100 Ameliorates Memory and Learning Impairments in a Mouse Model of Fragile X Syndrome.
1/2018HDAC6 is a therapeutic target in mutant GARS-induced Charcot-Marie-Tooth disease.
1/2017Synthesis of Potent and Selective HDAC6 Inhibitors Bearing a Cyclohexane- or Cycloheptane-Annulated 1,5-Benzothiazepine Scaffold.
2/2016Bicyclic-Capped Histone Deacetylase 6 Inhibitors with Improved Activity in a Model of Axonal Charcot-Marie-Tooth Disease.
8/2012Charcot-Marie-Tooth disease: emerging mechanisms and therapies.

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Veronick Benoy Research Topics

Disease

4Charcot-Marie-Tooth Disease (Peroneal Muscular Atrophy)
01/2018 - 08/2012
3Neurodegenerative Diseases (Neurodegenerative Disease)
01/2021 - 08/2012
3Peripheral Nervous System Diseases (PNS Diseases)
01/2018 - 08/2012
2Fragile X Syndrome (Martin Bell Syndrome)
01/2021 - 01/2019
2Neoplasms (Cancer)
01/2017 - 01/2017
1Type 2A Charcot-Marie-Tooth disease
01/2021
1Rupture
01/2020
1Rare Diseases (Rare Disease)
01/2019
1Type 2F Charcot-Marie-Tooth disease
02/2016

Drug/Important Bio-Agent (IBA)

6Histone Deacetylase 6IBA
01/2021 - 08/2012
2SW-100IBA
01/2021 - 01/2019
11,2,3,4-tetrahydroquinolineIBA
01/2021
1Cathepsin BIBA
01/2020
1PolyaminesIBA
01/2020
1Glycine-tRNA LigaseIBA
01/2018
1TubulinIBA
01/2018
1ricolinostatIBA
01/2017
1Pharmaceutical PreparationsIBA
01/2017
1tubastatin AIBA
02/2016

Therapy/Procedure

5Therapeutics
01/2019 - 08/2012